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Our ancient Rabbis, as with one voice, have declared that by the seed of the woman, who was to bruise the head of the serpent is meant the Messiah. You know as well as I, their common saying, “that before the serpent had wounded our first parents, God had prepared a plaster for their healing; and as soon as sin had made its entrance into our world, the Messiah had made his appearance.” Hence both the Targums, that of Onkelos, and that of Jonathan, say “that the voice which our first parents heard walking in the garden, was the Memra Jehovah, ie. the word of the Lord, or the Messiah, who is always meant by this expression;… In the Targum of Jonathan, and that of Jerusalem, it is said, “the seed of the woman shall bruise the head of the serpent, and they shall obtain healing, or a plaster for the heel, (the hurt received by the Serpent,) in the days of Messiah the King.”