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The 'it' is referring to 'all' in the phrase before.
A better translation is, "And this is the will of Him who sent me, that all that He hath given to me I may not lose of it, but may raise it up in the last day.
'It' is referring to the 'all' (which is bolded). I don't know why the ESV and the translation I refer to use 'it'. I'm not the translator.